Putting the brakes on mammary tumorigenesis: Loss of STAT1 predisposes to intraepithelial neoplasias

Multiparous Stat1(−/−) mice spontaneously develop mammary tumors with increased incidence: at an average age of 12 months, 55% of the animals suffer from mammary cancer, although the histopathology is heterogeneous. We consistently observed mosaic expression or down-regulation of STAT1 protein in wi...

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Detalhes bibliográficos
Main Authors: Schneckenleithner, Christine, Bago-Horvath, Zsuzsanna, Dolznig, Helmut, Neugebauer, Nina, Kollmann, Karoline, Kolbe, Thomas, Decker, Thomas, Kerjaschki, Dontscho, Wagner, Kay-Uwe, Müller, Mathias, Stoiber, Dagmar, Sexl, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282066/
https://ncbi.nlm.nih.gov/pubmed/22185785
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