Yüklüyor......
On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Type II topoisomerases (Top2s) alter DNA topology via the formation of an enzyme–DNA adduct termed cleavage complex, which harbors a transient double-strand break in one DNA to allow the passage of another. Agents targeting human Top2s are clinically active anticancer drugs whose trapping of Top2-me...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2013
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905874/ https://ncbi.nlm.nih.gov/pubmed/24038465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt828 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|