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Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment
Exposure to genotoxic agents, such as ionizing radiation (IR), produces double-strand breaks, repaired predominantly in mammalian cells by non-homologous end-joining (NHEJ). Ku70 was identified as an interacting partner of a proteolytic Cyclin E (CycE) fragment, p18CycE. p18CycE endogenous generatio...
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| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905870/ https://ncbi.nlm.nih.gov/pubmed/24021630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt812 |
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