Opening pathways of the DNA clamps proliferating cell nuclear antigen and Rad9-Rad1-Hus1

Proliferating cell nuclear antigen and the checkpoint clamp Rad9-Rad1-Hus1 topologically encircle DNA and act as mobile platforms in the recruitment of proteins involved in DNA damage response and cell cycle regulation. To fulfill these vital cellular functions, both clamps need to be opened and loa...

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Bibliographic Details
Main Authors: Xu, Xiaojun, Guardiani, Carlo, Yan, Chunli, Ivanov, Ivaylo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Computational Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905852/
https://ncbi.nlm.nih.gov/pubmed/24038358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt810
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