Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability

Processivity clamps such as proliferating cell nuclear antigen (PCNA) and the checkpoint sliding clamp Rad9/Rad1/Hus1 (9-1-1) act as versatile scaffolds in the coordinated recruitment of proteins involved in DNA replication, cell-cycle control, and DNA repair. Association and handoff of DNA-editing...

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Detalhes bibliográficos
Main Authors: Querol-Audí, Jordi, Yan, Chunli, Xu, Xiaojun, Tsutakawa, Susan E., Tsai, Miaw-Sheue, Tainer, John A., Cooper, Priscilla K., Nogales, Eva, Ivanov, Ivaylo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365210/
https://ncbi.nlm.nih.gov/pubmed/22586102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121116109
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