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Optochemical control of RNA interference in mammalian cells

Short interfering RNAs (siRNAs) and microRNAs (miRNAs) have been widely used in mammalian tissue culture and model organisms to selectively silence genes of interest. One limitation of this technology is the lack of precise external control over the gene-silencing event. The use of photocleavable pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Govan, Jeane M., Young, Douglas D., Lusic, Hrvoje, Liu, Qingyang, Lively, Mark O., Deiters, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905849/
https://ncbi.nlm.nih.gov/pubmed/24021631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt806
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