In vitro reconstitution of human replication factor C from its five subunits.

Replication factor C (RFC, also called Activator I) is part of the processive eukaryotic DNA polymerase holoenzymes. The processive elongation of DNA chains requires that DNA polymerases are tethered to template DNA at primer ends. In eukaryotes the ring-shaped homotrimeric protein, proliferating ce...

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Bibliographic Details
Main Authors: Uhlmann, F, Cai, J, Flores-Rozas, H, Dean, F B, Finkelstein, J, O'Donnell, M, Hurwitz, J
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC39056/
https://ncbi.nlm.nih.gov/pubmed/8692848
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