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ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits
Human replication factor C (hRFC) is a five-subunit protein complex (p140, p40, p38, p37, and p36) that acts to catalytically load proliferating cell nuclear antigen onto DNA, where it recruits DNA polymerase δ or ɛ to the primer terminus at the expense of ATP, leading to processive DNA synthesis. W...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21688/ https://ncbi.nlm.nih.gov/pubmed/9751713 |
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