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ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits

Human replication factor C (hRFC) is a five-subunit protein complex (p140, p40, p38, p37, and p36) that acts to catalytically load proliferating cell nuclear antigen onto DNA, where it recruits DNA polymerase δ or ɛ to the primer terminus at the expense of ATP, leading to processive DNA synthesis. W...

詳細記述

保存先:
書誌詳細
主要な著者: Cai, Jinsong, Yao, Nina, Gibbs, Emma, Finkelstein, Jeff, Phillips, Barbara, O’Donnell, Michael, Hurwitz, Jerard
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC21688/
https://ncbi.nlm.nih.gov/pubmed/9751713
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