Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen

Proliferating cell nuclear antigen (PCNA) is a processivity factor required for DNA polymerase δ (or ɛ)-catalyzed DNA synthesis. When loaded onto primed DNA templates by replication factor C (RFC), PCNA acts to tether the polymerase to DNA, resulting in processive DNA chain elongation. In this repor...

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Bibliographic Details
Main Authors: Zhang, Gang, Gibbs, Emma, Kelman, Zvi, O’Donnell, Michael, Hurwitz, Jerard
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC26703/
https://ncbi.nlm.nih.gov/pubmed/10051561
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