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Antibodies specific for amino acid 12 of the ras oncogene product inhibit GTP binding.

An antibody (anti-p21ser) was raised against a ras p21-related synthetic peptide and was able to recognize specifically the substitution of serine for glycine at amino acid 12 of p21. This substitution causes oncogenic activation of p21. Anti-p21ser was found to immunoprecipitate v-Ki-ras p21 and to...

詳細記述

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書誌詳細
主要な著者: Clark, R, Wong, G, Arnheim, N, Nitecki, D, McCormick, F
フォーマット: Artigo
言語:Inglês
出版事項: 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC390551/
https://ncbi.nlm.nih.gov/pubmed/3927300
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