The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress

The Y-box binding protein 1 (YB-1) is a DNA/RNA-binding nucleocytoplasmic shuttling protein whose regulatory effect on many DNA and RNA-dependent events is determined by its localization in the cell. We have shown previously that YB-1 is cleaved by 20S proteasome between E219 and G220, and the trunc...

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Hlavní autoři: Kim, Ekaterina R, Selyutina, Anastasia A, Buldakov, Ilya A, Evdokimova, Valentina, Ovchinnikov, Lev P, Sorokin, Alexey V
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905071/
https://ncbi.nlm.nih.gov/pubmed/24107631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26670
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