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DNA damage repair machinery and HIV escape from innate immune sensing

Viruses have been long known to perturb cell cycle regulators and key players of the DNA damage response to benefit their life cycles. In the case of the human immunodeficiency virus (HIV), the viral auxiliary protein Vpr activates the structure-specific endonuclease SLX4 complex to promote escape f...

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Detalhes bibliográficos
Main Authors: Brégnard, Christelle, Benkirane, Monsef, Laguette, Nadine
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001025/
https://ncbi.nlm.nih.gov/pubmed/24795708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00176
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