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A subset of 26S proteasomes is activated at critically low ATP concentrations and contributes to myocardial injury during cold ischemia

Molecular mechanisms leading to myocardial injury during warm or cold ischemia are insufficiently understood. Although proteasomes are thought to contribute to myocardial ischemia-reperfusion injury, their roles during the ischemic period remain elusive. Because donor hearts are commonly exposed to...

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Detalhes bibliográficos
Main Authors: Geng, Qing, Romero, Jacqueline, Saini, Vikas, Baker, Todd A., Picken, Maria M., Gamelli, Richard L., Majetschak, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904645/
https://ncbi.nlm.nih.gov/pubmed/19944202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.10.067
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