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Prostaglandin D(2) toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites
Prostaglandin D(2) (PGD(2)) is the most abundant prostaglandin in brain but its effect on neuronal cell death is complex and not completely understood. PGD(2) may modulate neuronal cell death via activation of DP receptors or its metabolism to the cyclopentenone prostaglandins (CyPGs) PGJ(2), Δ(12)-...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904641/ https://ncbi.nlm.nih.gov/pubmed/23973622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.08.001 |
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