Increased generation of cyclopentenone prostaglandins after brain ischemia and their role in aggregation of ubiquitinated proteins in neurons

The cyclopentenone prostaglandin (CyPG) J(2) series, including prostaglandin J(2) (PGJ(2)), Δ(12)-PGJ(2) and 15-deoxy-Δ(12, 14) -prostaglandin J(2) (15d-PGJ(2)), are active metabolites of PGD(2), exerting multiple effects on neuronal function. However, the physiologic relevance of these effects rema...

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Detalhes bibliográficos
Main Authors: Liu, Hao, Li, Wenjin, Ahmad, Muzamil, Rose, Marie E., Miller, Tricia M., Yu, Mei, Chen, Jie, Pascoe, Jordan L., Poloyac, Samuel M., Hickey, Robert W., Graham, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692569/
https://ncbi.nlm.nih.gov/pubmed/23355003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-013-9377-4
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