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Macrophage Phenotype Controls Long-Term AKI Outcomes—Kidney Regeneration versus Atrophy

The mechanisms that determine full recovery versus subsequent progressive CKD after AKI are largely unknown. Because macrophages regulate inflammation as well as epithelial recovery, we investigated whether macrophage activation influences AKI outcomes. IL-1 receptor–associated kinase-M (IRAK-M) is...

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Detalhes bibliográficos
Main Authors: Lech, Maciej, Gröbmayr, Regina, Ryu, Mi, Lorenz, Georg, Hartter, Ingo, Mulay, Shrikant R., Susanti, Heni Eka, Kobayashi, Koichi S., Flavell, Richard A., Anders, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904561/
https://ncbi.nlm.nih.gov/pubmed/24309188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013020152
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