IRF4 Deficiency Abrogates Lupus Nephritis Despite Enhancing Systemic Cytokine Production

The IFN-regulatory factors IRF1, IRF3, IRF5, and IRF7 modulate processes involved in the pathogenesis of systemic lupus and lupus nephritis, but the contribution of IRF4, which has multiple roles in innate and adaptive immunity, is unknown. To determine a putative pathogenic role of IRF4 in lupus, w...

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Bibliografiset tiedot
Päätekijät: Lech, Maciej, Weidenbusch, Marc, Kulkarni, Onkar P., Ryu, Mi, Darisipudi, Murthy Narayana, Susanti, Heni Eka, Mittruecker, Hans-Willi, Mak, Tak W., Anders, Hans-Joachim
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2011
Aiheet:
Basic Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148699/
https://ncbi.nlm.nih.gov/pubmed/21742731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010121260
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