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IRF4 Deficiency Abrogates Lupus Nephritis Despite Enhancing Systemic Cytokine Production
The IFN-regulatory factors IRF1, IRF3, IRF5, and IRF7 modulate processes involved in the pathogenesis of systemic lupus and lupus nephritis, but the contribution of IRF4, which has multiple roles in innate and adaptive immunity, is unknown. To determine a putative pathogenic role of IRF4 in lupus, w...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Nephrology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148699/ https://ncbi.nlm.nih.gov/pubmed/21742731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010121260 |
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