Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for IFNL3 (IL28B) Genotype and PEG Interferon-α–Based Regimens

Pegylated interferon-α (PEG-IFN-α or PEG-IFN 2a and 2b)– and ribavirin (RBV)-based regimens are the mainstay for treatment of hepatitis C virus (HCV) genotype 1. IFNL3 (IL28B) genotype is the strongest baseline predictor of response to PEG-IFN-α and RBV therapy in previously untreated patients and c...

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Bibliographische Detailangaben
Hauptverfasser: Muir, A J, Gong, L, Johnson, S G, Lee, M T M, Williams, M S, Klein, T E, Caudle, K E, Nelson, D R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
CPIC Guidelines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904555/
https://ncbi.nlm.nih.gov/pubmed/24096968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.203
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