Human cytidine deaminase: A biochemical characterization of its naturally occurring variants

Human cytidine deaminase is an enzyme of the pyrimidine salvage pathways that metabolizes several cytosine nucleoside analogs used as prodrugs in chemotherapy. We carried out a characterization of the cytidine deaminase 79A>C and 208G>A Single Nucleotide Polymorphisms, in order to highlight th...

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Main Authors: Micozzi, Daniela, Carpi, Francesco Martino, Pucciarelli, Stefania, Polzonetti, Valeria, Polidori, Paolo, Vilar, Santiago, Williams, Brian, Costanzi, Stefano, Vincenzetti, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904506/
https://ncbi.nlm.nih.gov/pubmed/24183806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2013.10.029
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