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Computation-Guided Discovery of Influenza Endonuclease Inhibitors

[Image: see text] Influenza is a global human health threat, and there is an immediate need for new antiviral therapies to circumvent the limitations of vaccination and current small molecule therapies. During viral transcription, influenza incorporates the 5′-end of the host cell’s mRNA in a proces...

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Autores principales: Chen, Eric, Swift, Robert V., Alderson, Nazilla, Feher, Victoria A., Feng, Gen-Sheng, Amaro, Rommie E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2013
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904387/
https://ncbi.nlm.nih.gov/pubmed/24490002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4003474
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