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Emerging Computational Methods for the Rational Discovery of Allosteric Drugs
[Image: see text] Allosteric drug development holds promise for delivering medicines that are more selective and less toxic than those that target orthosteric sites. To date, the discovery of allosteric binding sites and lead compounds has been mostly serendipitous, achieved through high-throughput...
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| 出版年: | Chem Rev |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2016
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4901368/ https://ncbi.nlm.nih.gov/pubmed/27074285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00631 |
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