Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells

The rapid differentiation of monocytes into macrophages (MΦ) and dendritic cells is a pivotal aspect of the innate immune response. Differentiation is triggered following recognition of microbial ligands that activate pattern recognition receptors or directly by pro-inflammatory cytokines. We demons...

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Bibliographische Detailangaben
Hauptverfasser: Schenk, Mirjam, Fabri, Mario, Krutzik, Stephan R, Lee, Delphine J, Vu, David M, Sieling, Peter A, Montoya, Dennis, Liu, Philip T, Modlin, Robert L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904238/
https://ncbi.nlm.nih.gov/pubmed/24032597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12167
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