Type I Interferon Suppresses Type II Interferon–Triggered Human Anti-Mycobacterial Responses

Type I interferons (IFN-α and IFN-β) are important for protection against many viral infections, whereas type II interferon (IFN-γ) is essential for host defense against some bacterial and parasitic pathogens. Study of IFN responses in human leprosy revealed an inverse correlation between IFN-β and...

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Hauptverfasser: Teles, Rosane M. B., Graeber, Thomas G., Krutzik, Stephan R., Montoya, Dennis, Schenk, Mirjam, Lee, Delphine J., Komisopoulou, Evangelia, Kelly-Scumpia, Kindra, Chun, Rene, Iyer, Shankar S., Sarno, Euzenir N., Rea, Thomas H., Hewison, Martin, Adams, John S., Popper, Stephen J., Relman, David A., Stenger, Steffen, Bloom, Barry R., Cheng, Genhong, Modlin, Robert L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653587/
https://ncbi.nlm.nih.gov/pubmed/23449998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1233665
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