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Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2

Channelrhodopsin-2 (ChR2) has quickly gained popularity as a powerful tool for eliciting genetically targeted neuronal activation. However, little has been reported on the response kinetics of optogenetic stimulation across different neuronal subtypes. With excess stimulation, neurons can be driven...

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Détails bibliographiques
Auteurs principaux: Herman, Alexander M, Huang, Longwen, Murphey, Dona K, Garcia, Isabella, Arenkiel, Benjamin R
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904216/
https://ncbi.nlm.nih.gov/pubmed/24473077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01481
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