Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2

Channelrhodopsin-2 (ChR2) has quickly gained popularity as a powerful tool for eliciting genetically targeted neuronal activation. However, little has been reported on the response kinetics of optogenetic stimulation across different neuronal subtypes. With excess stimulation, neurons can be driven...

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Bibliografiske detaljer
Main Authors: Herman, Alexander M, Huang, Longwen, Murphey, Dona K, Garcia, Isabella, Arenkiel, Benjamin R
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2014
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904216/
https://ncbi.nlm.nih.gov/pubmed/24473077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01481
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