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Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2

Channelrhodopsin-2 (ChR2) has quickly gained popularity as a powerful tool for eliciting genetically targeted neuronal activation. However, little has been reported on the response kinetics of optogenetic stimulation across different neuronal subtypes. With excess stimulation, neurons can be driven...

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Hlavní autoři: Herman, Alexander M, Huang, Longwen, Murphey, Dona K, Garcia, Isabella, Arenkiel, Benjamin R
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904216/
https://ncbi.nlm.nih.gov/pubmed/24473077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01481
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