CpG adjuvant enhances the mucosal immunogenicity and efficacy of a Treponema pallidum DNA vaccine in rabbits

Objectives: The protective response against Treponema pallidum (Tp) infection of a DNA vaccine enhanced by an adjuvant CpG ODN was investigated. Results: The mucosal adjuvant CpG ODN enhanced the production of higher levels of anti-TpGpd antibodies induced by pcD/Gpd-IL-2 in rabbits. It also resulte...

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Detalhes bibliográficos
Main Authors: Zhao, Feijun, Liu, Shuangquan, Zhang, Xiaohong, Yu, Jian, Zeng, Tiebing, Gu, Weiming, Cao, Xunyu, Chen, Xi, Wu, Yimou
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903891/
https://ncbi.nlm.nih.gov/pubmed/23563515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.23064
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