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Reprogramming somatic cells to pluripotency: A fresh look at Yamanaka’s model

In 2006, Dr Shinya Yamanaka succeeded to reprogram somatic cells into pluripotent stem cells (iPSC) by delivering the genes encoding Oct4, Sox2, Klf4, and c-Myc. This achievement represents a fundamental breakthrough in stem cell biology and opens up a new era in regenerative medicine. However, the...

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Detalhes bibliográficos
Main Authors: Li, Yangxin, Shen, Zhenya, Shelat, Harnath, Geng, Yong-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903711/
https://ncbi.nlm.nih.gov/pubmed/24189530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26952
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