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Reprogramming somatic cells to pluripotency: A fresh look at Yamanaka’s model
In 2006, Dr Shinya Yamanaka succeeded to reprogram somatic cells into pluripotent stem cells (iPSC) by delivering the genes encoding Oct4, Sox2, Klf4, and c-Myc. This achievement represents a fundamental breakthrough in stem cell biology and opens up a new era in regenerative medicine. However, the...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903711/ https://ncbi.nlm.nih.gov/pubmed/24189530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26952 |
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