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Oct4 Mediates Tumor Initiating Properties in Oral Squamous Cell Carcinomas through the Regulation of Epithelial-Mesenchymal Transition

BACKGROUND: Overexpression of Oct4, an important transcription factor of embryonic stem cells (ESC), has been reported in several cancers. The aim of this study was to determine the emerging role of Oct4 in oral squamous cell carcinoma (OSCC) both in vitro and in vivo. METHODOLOGY/PRINCIPAL FINDING:...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tsai, Lo-Lin, Hu, Fang-Wei, Lee, Shiuan-Shinn, Yu, Chuan-Hang, Yu, Cheng-Chia, Chang, Yu-Chao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903644/
https://ncbi.nlm.nih.gov/pubmed/24475251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087207
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