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Elevated Snail Expression Mediates Tumor Progression in Areca Quid Chewing-Associated Oral Squamous Cell Carcinoma via Reactive Oxygen Species

BACKGROUND: Snail is an important transcription factor implicated in several tumor progression and can be induced by reactive oxygen species (ROS). Areca quid chewing is a major risk factor of oral squamous cell carcinoma (OSCC). Therefore, we hypothesize that the major areca nut alkaloid arecoline...

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Detalhes bibliográficos
Main Authors: Lee, Shiuan-Shinn, Tsai, Chung-Hung, Yu, Cheng-Chia, Chang, Yu-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707908/
https://ncbi.nlm.nih.gov/pubmed/23874481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067985
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