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Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline

Oral squamous cell carcinoma (OSCC), one of the most deadliest malignancies in the world, is caused primarily by areca nut chewing in Southeast Asia. The mechanisms by which areca nut participates in OSCC tumorigenesis are not well understood. In this study, we investigated the effects of low dose l...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Tung Yuan, Peng, Chih-Yu, Lee, Shiuan-Shinn, Chou, Ming-Yung, Yu, Cheng-Chia, Chang, Yu-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356645/
https://ncbi.nlm.nih.gov/pubmed/27557511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11432
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