Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline

Oral squamous cell carcinoma (OSCC), one of the most deadliest malignancies in the world, is caused primarily by areca nut chewing in Southeast Asia. The mechanisms by which areca nut participates in OSCC tumorigenesis are not well understood. In this study, we investigated the effects of low dose l...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wang, Tung Yuan, Peng, Chih-Yu, Lee, Shiuan-Shinn, Chou, Ming-Yung, Yu, Cheng-Chia, Chang, Yu-Chao
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356645/
https://ncbi.nlm.nih.gov/pubmed/27557511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11432
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