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MUSCLE: multiple sequence alignment with high accuracy and high throughput

We describe MUSCLE, a new computer program for creating multiple alignments of protein sequences. Elements of the algorithm include fast distance estimation using kmer counting, progressive alignment using a new profile function we call the log-expectation score, and refinement using tree-dependent...

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Detaylı Bibliyografya
Yazar: Edgar, Robert C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC390337/
https://ncbi.nlm.nih.gov/pubmed/15034147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh340
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