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MUSCLE: multiple sequence alignment with high accuracy and high throughput
We describe MUSCLE, a new computer program for creating multiple alignments of protein sequences. Elements of the algorithm include fast distance estimation using kmer counting, progressive alignment using a new profile function we call the log-expectation score, and refinement using tree-dependent...
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| Format: | Artigo |
| Jezik: | Inglês |
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Oxford University Press
2004
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390337/ https://ncbi.nlm.nih.gov/pubmed/15034147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh340 |
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