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Multiple sequence alignment accuracy and evolutionary distance estimation

BACKGROUND: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pair wise sequence alignment, but this assumption has rarely been tested, and never with the control provided by simulation...

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Detalhes bibliográficos
Autor principal: Rosenberg, Michael S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1318491/
https://ncbi.nlm.nih.gov/pubmed/16305750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-278
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