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Multiple sequence alignment accuracy and evolutionary distance estimation

BACKGROUND: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pair wise sequence alignment, but this assumption has rarely been tested, and never with the control provided by simulation...

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Bibliografiske detaljer
Hovedforfatter: Rosenberg, Michael S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1318491/
https://ncbi.nlm.nih.gov/pubmed/16305750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-278
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