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Analysis of chromatin-state plasticity identifies cell-type–specific regulators of H3K27me3 patterns

Chromatin states are highly cell-type–specific, but the underlying mechanisms for the establishment and maintenance of their genome-wide patterns remain poorly understood. Here we present a computational approach for investigation of chromatin-state plasticity. We applied this approach to investigat...

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Detalhes bibliográficos
Main Authors: Pinello, Luca, Xu, Jian, Orkin, Stuart H., Yuan, Guo-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903219/
https://ncbi.nlm.nih.gov/pubmed/24395799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322570111
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