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Homologous gene targeting in Caenorhabditis elegans by biolistic transformation

Targeted homologous recombination is a powerful approach for genome manipulation that is widely used for gene alteration and knockouts in mouse and yeast. In Caenorhabditis elegans, several methods of target-selected mutagenesis have been implemented but none of them provides the opportunity of intr...

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Autors principals: Berezikov, Eugene, Bargmann, Cornelia I., Plasterk, Ronald H. A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC390312/
https://ncbi.nlm.nih.gov/pubmed/14982959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh033
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