Efficient target-selected mutagenesis in Caenorhabditis elegans: Toward a knockout for every gene

Reverse genetic or gene-driven knockout approaches have contributed significantly to the success of model organisms for fundamental and biomedical research. Although various technologies are available for C. elegans, none of them scale very well for genome-wide application. To address this, we imple...

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Detalhes bibliográficos
Main Authors: Cuppen, Edwin, Gort, Eelke, Hazendonk, Esther, Mudde, Josine, van de Belt, José, Nijman, Isaäc J., Guryev, Victor, Plasterk, Ronald H.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855173/
https://ncbi.nlm.nih.gov/pubmed/17416746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6080607
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