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High-Throughput Screening to Identify Plant Derived Human LDH-A Inhibitors

AIMS: Lactate dehydrogenase (LDH)-A is highly expressed in diverse human malignant tumors, parallel to aggressive metastatic disease, resistance to radiation/chemotherapy and clinically poor outcome. Although this enzyme constitutes a plausible target in treatment of advanced cancer, there are few k...

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Autori principali: Deiab, S., Mazzio, E., Messeha, S., Mack, N., Soliman, K. F. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903096/
https://ncbi.nlm.nih.gov/pubmed/24478981
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