Llwytho...

Quantitative influence of macromolecular crowding on gene regulation kinetics

We introduce macromolecular crowding quantitatively into the model for kinetics of gene regulation in Escherichia coli. We analyse and compute the specific-site searching time for 180 known transcription factors (TFs) regulating 1300 operons. The time is between 160 s (e.g. for SoxS M(w) = 12.91 kDa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tabaka, Marcin, Kalwarczyk, Tomasz, Hołyst, Robert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902910/
https://ncbi.nlm.nih.gov/pubmed/24121687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt907
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