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How can macromolecular crowding inhibit biological reactions? The enhanced formation of DNA nanoparticles
In contrast to the already known effect that macromolecular crowding usually promotes biological reactions, solutions of PEG 6k at high concentrations stop the cleavage of DNA by HindIII enzyme, due to the formation of DNA nanoparticles. We characterized the DNA nanoparticles and probed the prerequi...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4763241/ https://ncbi.nlm.nih.gov/pubmed/26903405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22033 |
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