Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells

Modulation of miR-33 and miR-122 has been proposed to be a promising strategy to treat dyslipidemia and insulin resistance associated with obesity and metabolic syndrome. Interestingly, specific polyphenols reduce the levels of these mi(cro)RNAs. The aim of this study was to elucidate the effect of...

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Bibliographische Detailangaben
Hauptverfasser: Baselga-Escudero, Laura, Blade, Cinta, Ribas-Latre, Aleix, Casanova, Ester, Suárez, Manuel, Torres, Josep Lluís, Salvadó, M. Josepa, Arola, Lluis, Arola-Arnal, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Gene Regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902894/
https://ncbi.nlm.nih.gov/pubmed/24165878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1011
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