Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells

Modulation of miR-33 and miR-122 has been proposed to be a promising strategy to treat dyslipidemia and insulin resistance associated with obesity and metabolic syndrome. Interestingly, specific polyphenols reduce the levels of these mi(cro)RNAs. The aim of this study was to elucidate the effect of...

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Bibliografske podrobnosti
Main Authors: Baselga-Escudero, Laura, Blade, Cinta, Ribas-Latre, Aleix, Casanova, Ester, Suárez, Manuel, Torres, Josep Lluís, Salvadó, M. Josepa, Arola, Lluis, Arola-Arnal, Anna
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Gene Regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902894/
https://ncbi.nlm.nih.gov/pubmed/24165878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1011
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