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Kinetics and Thermodynamics of Phenotype: Unwinding and Rewinding the Nucleosome
Chromatin “remodeling” is widely accepted as the mechanism that permits access to DNA by the transcription machinery. To date, however, there has been no experimental measurement of the changes in the kinetics and thermodynamics of the DNA–histone octamer association that are required to remodel chr...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902851/ https://ncbi.nlm.nih.gov/pubmed/22944905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.08.021 |
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