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Kinetics and Thermodynamics of Phenotype: Unwinding and Rewinding the Nucleosome

Chromatin “remodeling” is widely accepted as the mechanism that permits access to DNA by the transcription machinery. To date, however, there has been no experimental measurement of the changes in the kinetics and thermodynamics of the DNA–histone octamer association that are required to remodel chr...

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Detalhes bibliográficos
Main Authors: Mack, Andrew H., Schlingman, Daniel J., Ilagan, Robielyn P., Regan, Lynne, Mochrie, Simon G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902851/
https://ncbi.nlm.nih.gov/pubmed/22944905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.08.021
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