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A new method for the covalent attachment of DNA to a surface for single-molecule studies

Attachments between DNA and a surface or bead are often necessary for single-molecule studies of DNA and DNA-protein interactions. In single-molecule mechanical studies using optical or magnetic tweezers, such attachments must be able to withstand the applied forces. Here we present a new method for...

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Detalhes bibliográficos
Main Authors: Schlingman, Daniel J., Mack, Andrew H., Mochrie, Simon G.J., Regan, Lynne
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902852/
https://ncbi.nlm.nih.gov/pubmed/21130613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.colsurfb.2010.11.002
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