Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target

PURPOSE: Patients with Neurofibromatosis Type 1 (NF1) develop malignant peripheral nerve sheath tumors (MPNST) which are often inoperable and do not respond well to current chemotherapies or radiation. The goal of this study was to utilize comprehensive gene expression analysis to identify novel the...

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Autors principals: Patel, Ami V., Eaves, David, Jessen, Walter J., Rizvi, Tilat A., Ecsedy, Jeffrey A., Qian, Mark G., Aronow, Bruce J., Perentesis, John P., Serra, Eduard, Cripe, Timothy P., Miller, Shyra J., Ratner, Nancy
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902639/
https://ncbi.nlm.nih.gov/pubmed/22811580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1072
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