Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target

PURPOSE: Patients with Neurofibromatosis Type 1 (NF1) develop malignant peripheral nerve sheath tumors (MPNST) which are often inoperable and do not respond well to current chemotherapies or radiation. The goal of this study was to utilize comprehensive gene expression analysis to identify novel the...

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Hauptverfasser: Patel, Ami V., Eaves, David, Jessen, Walter J., Rizvi, Tilat A., Ecsedy, Jeffrey A., Qian, Mark G., Aronow, Bruce J., Perentesis, John P., Serra, Eduard, Cripe, Timothy P., Miller, Shyra J., Ratner, Nancy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902639/
https://ncbi.nlm.nih.gov/pubmed/22811580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1072
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